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Relationship between the properties of an amino acid and its prevalence among library 1 prion-forming isolates. ln (ORobs) for each amino acid in library 1 (from Table 2) plotted versus hydrophobicity (A), β-sheet propensity (B) (lower values represent greater β-sheet propensities), α-helix propensity (C) (lower values represent greater α-helix propensities), or ln (ORest) (D). P values were calculated by Spearman's rank correlation. Error bars represent 95% confidence intervals.
