FIG. 5.

Muscle-specific JNK1 deficiency causes increased diet-induced hepatic steatosis. (A) Chow-fed (ND) and HFD-fed (HF) M^WT and M^KO mice were fasted overnight. Representative sections of the liver stained with hematoxylin and eosin are presented. Scale bar, 100 μm. (B) The amount of hepatic triglyceride was measured in mice fasted overnight (means ± SD) (n = 10). Statistically significant differences between M^KO and M^WT are indicated (*, P < 0.05; **, P < 0.01).