The G92 Globular Structures Do Not Form Isolated Clusters of Membranes.
FRAP analyses of the ER soluble marker, ER-yb, within the entire globular structure (arrowhead) in G92 cells expressing the marker shows recovery of fluorescence upon photobleaching, indicating that the structure is not an isolated mass of membranes and that it is continuous with the ER. Time points of the recovery phase from the bleach event are indicated in the bottom left corner of frames. Bar = 10 μm.