TABLE 2.
Fold change in mRNA levels for selected target genes
| Gene | Fold change |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 3-h arraysb |
3-h qRT-PCRc |
6-h arraysb |
6-h qRT-PCRc |
||||||
| NaB | TSA | TSA dupd | NaB | TSA | NaB | TSA | NaB | TSA | |
| IER3 gene | 4.9 | 5.7 | 2.8 | 4.6 | 4.1 | 6.1 | 7.5 | 12.5 | 9.7 |
| Stat3 gene | 2.8 | 3 | 2.8 | 2.2 | 2.6 | 5.6 | 6.1 | 5.1 | 8.1 |
| Fos gene | 18.4a | 18.4a | 9.2 | 6.7 | 11.1 | 9.2a | 8.6 | 10.4 | 12.4 |
| SEPP1 gene | 3.7 | 4.9 | 4.6 | 4.3 | 6 | 9.2 | 11.3 | 12.2 | 16.8 |
| C1ORF38 gene | 4 | 4 | 5.6 | 4.3 | 2.1 | 9.2a | 9.2a | 6.4 | 8.2 |
| C13ORF25 gene | −6.1 | −7 | −5.6 | −4.3 | −4 | −6.5 | −7 | −9.3 | −10.1 |
| ZFP91 gene | −3.5 | −3.7 | −2.3 | −1.4 | −1.1 | −4.9 | −7 | −3 | −2.9 |
a
Detection of transcript was an absent to present (untreated versus treated) call based on Affymetrix GCOS analysis. All other values were determined as present in both untreated and treated samples.
b
Pooled biological triplicates.
c
Mean values of technical triplicates.
d
TSA dup, biological duplicate of a 3-hour array experiment for TSA.