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HBV-transfected cells show a siRNA dose-dependent increase in sensitivity to SPDCA. Huh7T cells were transfected with P13 and cotransfected with increasing doses of the HBV siRNA 2791. Apoptosis was quantified by flow cytometry analysis of annexin V staining after treatment of cells with BFA-CHX-Z-VAD. Apoptotic cells are represented by peaks with higher fluorescence. The percentage of apoptotic cells is indicated.
