TABLE 1.

Mutations in ZEBOV GPΔMuc that confer resistance to CatB inhibitor CA074

Amino acid change in EBOV GPΔMuc	Corresponding codon changea	No. of clonesb
N40H	AAT to CAT	2
N40K	AAT to AAG	3
N40S	AAT to AGT	7
N40T	AAT to ACT	2
N40Y	AAT to TAT	1
T42A	ACA to GCA	1
L43F	TTA to TTC	1
D47V	GAT to GTT	1
I584F	ATC to TTC	1
K588R	AAG to AGG	10

^aNucleotide changes are underlined and in bold.

^bNumber of viral isolates from independent selections bearing this amino acid change.