(A) Viral load and absolute CD4+ T-cell count in SHIVSF162P3N i.r. inoculated macaques. +, time of euthanasia. (B) Percentages of CD4+ T cells in the colonic (Col), inguinal (Ing), and mesenteric (Mes) lymph nodes and IELs and LPLs from the jejunum during acute infection (week 2 or 3) and at time necropsy of macaques DN57, DG08, and DR16 are shown. Baseline values generated from three uninfected macaques are used for reference (100% values), with error bars indicating standard deviations.