TABLE 2.

Summary of sites of localization for CXCR4-using variants in R5 SHIV_SF162P3N-infected switch macaques

Animal	Infection route	Tropism variant	Localization of variant in the indicated tissuea
			Primary tissue		Secondary tissue
					LNs					Spl	GALT
			Thy	BM	Ax	Ili	Ing	Col			IEL	LPL
BR24b	i.v.	X4	NA	NA	+	+	+	+	+	−	−	−
CA28c	i.v.	X4	−	NA	+	+	+	−	−	+	−	−
DG08d	i.r.	X4	−	−	+	+	+	+	+	−	−	−
		Dual	−	+	+	+	+	−	+	+	−	+
DR16d	i.r.	Dual	+	+	+	+	+	+	+	+	+	+

^aThe presence (+) or absence (−) of the indicated variant was determined by envelope sequence analysis. NA, not available; Thy, thymus; BM, bone marrow; Ax, axillary; Ili, iliac; Ing, inguinal; Col, colonic; Mes, mesenteric; Spl, spleen; GALT, gut-associated lymphoid tissues.

^bTasca et al. (63).

^cHo et al. (29); also unpublished data.

^dThis study.