TABLE 3.
Antigenicities of A/CA/7/09 HA variants
| Infecting virus | Antibody titera in serum of ferrets immunized with: |
|||
|---|---|---|---|---|
| A/CA/4/09 WT | A/CA/4/09 ca 223R (V3) | A/CA/7/09 ca 222G (V5) | A/CA/7/09 ca 223R (V6) | |
| CA04 V3 | 8,192 | 1,024 | 2,048 | 1,024 |
| CA07 V5 | 8,192 | 1,024 | 1,024 | 1,024 |
| CA07 V6 | 4,096 | 1,024 | 1,024 | 512 |
| V5-119N | 8,192 | 512 | 2,048 | 1,024 |
| V5-119E | 4,096 | 512 | 1,024 | 512 |
| V5-153E | 256 | <32 | 128 | 64 |
| V5-154E | 512 | <32 | 128 | 128 |
| V5-155E | 256 | <32 | 128 | 128 |
| V5-186D | 8,192 | 1,024 | 2,048 | 1,024 |
| V5-278K | 4,096 | 512 | 1,024 | 512 |
| V5-119E/186D | 8,192 | 1,024 | 2,048 | 1,024 |
a
HAI assay was performed with tRBCs. Each value is the reciprocal of the highest serum dilution that inhibited hemagglutination. Bold font indicates homologous. ca, cold adapted.