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Relative activities of fluoroquinolones
| Assay result | Rank order of activitya |
|||
|---|---|---|---|---|
| D (8-OMe; 7-N Et) | F (8-OMe; 7-C Et) | K (8-H; 7-N Et) | I (8-H; 7-C Et) | |
| Restricts recovery of mutants on agar (Fig. 5) | 1 | 2 | 3 | 4 |
| Lethality in liquid (MBC; Table 2) | 1 | 2 | 3 | 4 |
| Lethality on agar surface (Fig. 6) | 1 | 4 | 3 | 2 |
| Restricts gyrase mutant growth (Fig. 7) | 1 | 2 | 4 | 3 |
| Restricts mutant subpopulation growth (Fig. 8) | 2 | 1 | 4 | 3 |
OME, methoxy; Et, ethyl.
