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. 2009 Nov 9;54(1):328–332. doi: 10.1128/AAC.00961-09

FIG. 2.

FIG. 2.

Dendrogram obtained for 13 representative class A β-lactamases by neighbor-joining analysis. The alignment used for the tree calculation was performed with the ClustalX program. Branch lengths are drawn to scale and are proportional to the number of amino acid changes. The distance along the vertical axis has no significance. Numbers in parentheses indicate percentages of amino acid identity with the β-lactamase BIC-1. The β-lactamases (GenBank accession numbers indicated) are CARB-2 (Q0370), TEM-1 (AAG47772), SHV-1 (AAD18054), VEB-1 (AAK14293), PER-1 (CAF18433), CTX-M-1 (CAJ01342), KPC-2 (AAO53443), SFC-1 (AAR06587), SME-1 (CAA82281), NMC-A (CAA79967), GES-1 (AAL82589), and BEL-1 (AAZ04368).