TABLE 2.
MICs of β-lactams for P. fluorescens PF-1, E. coli DH10B harboring recombinant plasmid pSauI, and the E. coli DH10B reference strain
| β-Lactam(s) | MIC (μg/ml) |
||
|---|---|---|---|
| P. fluorescens PF-1 | E. coli DH10B (pSauI)a | E. coli DH10B | |
| Amoxicillin | >256 | >256 | 4 |
| Amoxicillin + CLAb | >256 | 16 | 4 |
| Ticarcillin | >256 | >256 | 4 |
| Ticarcillin + CLA | >256 | 128 | 4 |
| Piperacillin | 4 | 256 | 1 |
| Cephalothin | >256 | 128 | 2 |
| Cefuroxime | >256 | 16 | 0.5 |
| Cefoxitin | >256 | 4 | 1 |
| Ceftazidime | 2 | 0.5 | 0.5 |
| Cefotaxime | >32 | 0.5 | 0.12 |
| Cefepime | >16 | 0.12 | 0.06 |
| Moxalactam | >256 | 0.12 | 0.12 |
| Aztreonam | >256 | 16 | 0.25 |
| Imipenem | >16 | 2 | 0.12 |
| Imipenem + CLA | >16 | 0.25 | 0.12 |
| Meropenem | >16 | 0.25 | 0.12 |
| Ertapenem | >16 | 0.25 | 0.12 |
a
E. coli DH10B(pSau1) expressed β-lactamase BIC-1 from P. fluorescens PF-1.
b
CLA, clavulanic acid at a fixed concentration of 4 μg/ml.