TABLE 1.
Adverse events reported by two or more subjects during the single-dose study with S/GSK1349572
| AE | No. (%) of AEs with the following dosea: |
||||||
|---|---|---|---|---|---|---|---|
| 2 mg (n = 8) | 5 mg (n = 7) | 10 mg (n = 8) | 25 mg (n = 8) | 50 mg (n = 6) | 100 mg (n = 5) | Placebo (n = 5) | |
| Any AE | 2 (25) | 1 (14) | 2 (25) | 3 (38) | 3 (50) | 2 (40) | 3 (60) |
| Headache | 1 (13) | 0 | 1 (13) | 0 | 0 | 0 | 2 (40) |
| Somnolence | 0 | 0 | 0 | 0 | 2 (33) | 0 | 0 |
| Drug-related AE | 0 | 0 | 1 (13) | 3 (38) | 3 (50) | 0 | 1 (20) |
| Headache | 0 | 0 | 1 (13) | 0 | 0 | 0 | 1 (20) |
| Somnolence | 0 | 0 | 0 | 0 | 2 (33) | 0 | 0 |
n, number of subjects.