TABLE 1.
Comparison of mosaic PBP2-containing N. gonorrhoeae strains found in Sydney, Australia, in 2007 and 2008 with those detected in 2001 to 2005a
| Yr of isolation | No. of isolates with mosaic PBP2/total no. of isolates (%) in: |
Total no. (%) of isolates with mosaic PBP2 | NG-MAST | No. of isolates with indicated ST | Ceftriaxone MIC (μg/ml) | |
|---|---|---|---|---|---|---|
| Sequential sample | Selected sample | |||||
| 2001-2005 | 13 (NA) | 13 (NA) | 835 | 4 | 0.06 | |
| 1414 | 3 | 0.06 | ||||
| 1424 | 2 | 0.06 | ||||
| 2453 | 2 | 0.06 | ||||
| 326 | 1 | 0.06 | ||||
| 1677 | 1 | 0.06 | ||||
| 2007 | 0/60 (0) | 15 (1.5) | 15 (1.5) | 1407 | 9 | 0.016-0.06 |
| 3158 | 4 | 0.016-0.03 | ||||
| 3380 | 1 | 0.03 | ||||
| 3505 | 1 | 0.06 | ||||
| 2008 | 6/60 (10) | 79 (73) | 85 (10.3) | 1407 | 35 | 0.016-0.06 |
| 3149 | 26 | 0.016-0.06 | ||||
| 3158 | 13 | 0.016-0.03 | ||||
| 3159 | 2 | 0.03 | ||||
| 3161 | 2 | 0.03 | ||||
| 3168 | 2 | 0.03 | ||||
| 3294 | 2 | 0.016 | ||||
| 2955 | 1 | 0.03 | ||||
| 3381 | 1 | 0.016 | ||||
| 3380 | 1 | 0.03 | ||||
a
Data for isolates from 2001 to 2005 are from reference 20. A sequential sample of 60 nonduplicate isolates collected in 2007 and 2008 and a selected sample of isolates with an extended phenotype collected in 2007 and 2008 were examined for the presence of mPBP2GC. STs were determined by NG-MAST genotyping (10). All isolates listed in the table had the Pro[minus] (proline-requiring) auxotype. NA, not applicable.