. 2009 Nov 2;54(1):405–410. doi: 10.1128/AAC.00682-09

TABLE 3.

Pharmacodynamic parameters of nemonoxacin

Pathogen (no. of isolates)^a	MIC₉₀^b (μg/ml)	500 mg nemonoxacin^c
Pathogen (no. of isolates)^a	MIC₉₀^b (μg/ml)	fAUC/MIC₉₀	fC_max/MIC₉₀
S. pneumoniae (655)	0.015	1812	191
Penicillin-S S. pneumoniae (519)	0.015	1812	191
Penicillin-I S. pneumoniae (103)	0.015	1812	191
Penicillin-R S. pneumoniae (33)	0.03	906	95
Ciprofloxacin-R S. pneumoniae (29)	0.12	227	24
Methicillin-S S. aureus (375)	0.12	227	24
Methicillin-R S. aureus (26)	0.06	453	48

S, sensitive; I, intermediate; R, resistant.

Data from in vitro studies (28, 39).

fAUC, free AUC; fC_max, free C_max.