TABLE 6.
Effects of metallic salts on the antimicrobial activities of HL9 and HLopt2 against E. coli O6K5 and C. albicans 1800a
| Salinity or metallic salt | mM | 99% killing activityb |
|||
|---|---|---|---|---|---|
|
E. coli |
C. albicans |
||||
| HL9 | HLopt2 | HL9 | HLopt2 | ||
| Salinity | |||||
| NaCl | 25 | + | + | + | + |
| NaCl | 50 | + | + | + | + |
| NaCl | 100 | − | − | − | − |
| Metallic salts | |||||
| KCl | 25 | + | + | + | + |
| KCl | 50 | + | + | + | + |
| KCl | 100 | − | + | − | − |
| MgCl2 | 1 | + | + | + | + |
| MgCl2 | 2.5 | − | + | + | + |
| MgCl2 | 5.0 | − | − | − | + |
| CaCl2 | 1 | − | + | − | + |
| CaCl2 | 2.5 | − | − | − | − |
| CaCl2 | 5.0 | − | − | − | − |
a
Both peptides were analyzed at a concentration of 100 μg/ml. The salts were added to BP. All samples were run in triplicate.
b
+, ≥99% killing of the inoculum; −, <99% killing.