TABLE 6.
Enrichment analysis for functional categoriesa among the 120 transcriptionally upregulated genes in response to 0.2 g liter−1 iso-α-acid-enriched hop extract in anaerobic carbon-limited chemostat culture
| Database and functional category | No. of genes in: |
P value | Genes | |
|---|---|---|---|---|
| Module (total n = 120) | Genome (total n = 6,384) | |||
| GO, iron ion transport | 6 | 32 | 2.1 × 10−5 | AFT1, SIT1, FIT1, FIT2, FIT3, FET3 |
| MIPS | ||||
| 32. Cell rescue, defense, and virulence | 3 | 559 | 5.2 × 10−8 | RTA1, PDR16, FET3 |
| 32.01. Stress response | 17 | 454 | 1.3 × 10−5 | AHP1, PIR1, PIR3, HMS2, PAU7, CLN3, TIR3, SOD2, PAU1, WWM1, PAU2, SED1, SNQ2, RAD59, YBR016W, PIN4, YGP1 |
| 32.01.03. Osmotic and salt stress responses | 7 | 59 | 1.8 × 10−4 | VRP1, RRD1, HSP12, ISC1, GPD1, LAS17, GRE2 |
| 32.07. Detoxification | 9 | 119 | 7.0 × 10−4 | AHP1, TPO1, SOD2, AZR1, SIT1, SNQ2, SRL1, PDR5, GRE2 |