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. 2009 Dec 1;120(1):115–126. doi: 10.1172/JCI39721

Figure 5. Effects of C/EBPβ on ER stress and apoptosis in pancreatic β cells.

Figure 5

(A) Islets isolated from 8-week-old mice of the indicated genotypes were subjected to immunoblot analysis with antibodies to the indicated proteins. p-c-Jun and p-eIF2α represent phosphorylated forms of c-Jun and eIF2α, respectively. (B) Islets from 8-week-old mice of the indicated genotypes were incubated in RPMI 1640 medium for 24 hours, after which internucleosomal DNA fragmentation was examined by ligation-mediated PCR analysis.