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. 2010 Jan 5;5(1):e8581. doi: 10.1371/journal.pone.0008581

Figure 3. A significant number of Chk1+/− mice become anemic with age.

Figure 3

(A) Kaplan-Meier plot showing the incidence of anemia in the Chk1+/− mice compared to WT mice. A log-rank (Mantel-Cox) test was used to measure significance (p<0.05). Complete blood counts were done on 52-week-old WT and anemic Chk1+/− mice and significance was established by a student's t-test. (B) White blood counts (WBC), (C) platelet counts, and (D) red blood cell parameters (red blood cell counts, (RBC), hemoglobin (Hgb), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) are shown. A student's t-test was used to determine significance; an asterisk indicates a p<0.05.