Figure 4. Anemic Chk1+/− mice exhibit severe defects in several stages of erythropoiesis.

(A) Representative flow cytometry plots showing CD71 and Ter-119 staining used to separate the stages of erythropoiesis for WT and Chk1+/− mice. (B) The MEP and stages I–IV of erythropoiesis were analyzed via flow cytometry from the whole bone marrow of anemic Chk1+/− mice and 52-week-old WT mice. A student's t-test was used to determine significance; an asterisk indicates a p<0.05.