Table 2. Chk1+/ā show defective CAR formation.
Total Cells per type | Wt Cells w/defective CAR | Chk1+/ā Cells w/defective CAR | Fischer's Exact test | |
Stage I | 300 | 0 | 10 | Pā=ā0.0017 |
Stage IV | 300 | 4 | 59 | P<0.0001 |
Total | 600 | 4 | 69 | P<0.0001 |
Erythroid cells (Stage I and IV) were examined for defective CAR formation by immunohistiochemistry. Significant differences were calculated by Fisher's exact test.