Table 3.

Acute GVHD in patients receiving ¹³¹I-BC8/FLU/TBI and HLA-matched related and unrelated allogeneic transplants for advanced AML and high-risk MDS

	AML (n = 28)		Secondary AML (n = 19)	MDS* (n = 11)	All patients (n = 58)
	REM	REF/REL
Acute GVHD overall grade
Grade II	4 (14)	12 (43)	12 (63)	5 (45)	33 (57)
Grade III	5 (18)	0 (0)	4 (21)	1 (9)	10 (17)
Grade IV	0 (0)	0 (0)	0 (0)	1 (9)	1 (2)
Acute GVHD, gut
Grade II	1 (4)	1 (7)	3 (16)	1 (9)	6 (10)
Grade III	5 (18)	6 (40)	5 (26)	5 (45)	21 (36)
Grade IV	0 (0)	0 (0)	0 (0)	0 (0)	1 (0)
Acute GVHD, skin
Grade II	1 (4)	0 (0)	1 (5)	0 (0)	2 (4)
Grade III	1 (4)	0 (0)	1 (5)	1 (9)	3 (5)
Grade IV	0 (0)	0 (0)	0 (0)	1 (9)	1 (2)
Acute GVHD, liver
Grade II	0 (0)	0 (0)	2 (11)	1 (9)	3 (5)
Grade III	1 (4)	0 (0)	1 (5)	1 (9)	3 (5)
Grade IV	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)

Values are n (%).

REM indicates remission; REF/REL, refractory/relapsed.

^*MDS includes refractory anemia with excess of blasts and chronic myelomonocytic leukemia.