Figure 1. Embryonic lethality in Fancd2/Mlh1 double mutant mice.
Image of embryos around 12 dpc depicting a representative litter from Fancd2/Mlh1 double heterozygous breeding pairs. The severely underdeveloped Fancd2/Mlh1 double mutant is undergoing absorption. In this litter the Fancd2 mutant Mlh1 heterozygous embryo also shows developmental defects. Respective genotypes are indicated; HET: heterozygous, MUT: mutant.