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. Author manuscript; available in PMC: 2010 Dec 14.
Published in final edited form as: Cancer Res. 2009 Dec 15;69(24):9431–9438. doi: 10.1158/0008-5472.CAN-09-2452

Figure 2. Clonal survival of primary fribroblasts in addition of MMC.

Figure 2

Fancd2 mutant fibroblasts display a characteristic FA-like hypersensitivity to MMC. Additional inactivation of Mlh1 does not alter the MMC sensitivity of Fancd2 mutant primary fibroblasts. Fancd2/Mlh1 double heterozygous (-×-), double mutant (-□-), Fancd2 heterozygous Mlh1 mutant (-•-), and Fancd2 mutant Mlh1 heterozygous (-Δ-), error bars indicate standard error.