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. Author manuscript; available in PMC: 2010 Dec 14.
Published in final edited form as: Cancer Res. 2009 Dec 15;69(24):9431–9438. doi: 10.1158/0008-5472.CAN-09-2452

Figure 4. MlH1 increases chromosomal aberrations in immortal fibroblasts after exposure to MMC or DEB.

Figure 4

A, B) Frequencies of chromosomal interchanges after 48 hr of continuous exposure to 0, 5 or 15 ng/ml MMC or 0, 50 or 100 ng/ml DEB. 1 At 100 ng/ml DEB excessive chromosomal damage was observed in one of the averaged experiments and the outcome was set to 100% chromosomal aberrations which is an underrepresentation of the actual damage level. +: complemented with FANCD2 or MLH1, -: mock complemented, error bars indicate standard error.