Table 4.
Patients: Areas of Normalized rCBF Correlated to Generation Scores (p < 005)
| Condition | Brain region or Brodmann’s area (BA) |
Talairach coordinates X, Y, Z |
Voxels | r |
|---|---|---|---|---|
| EARLY: Block 2 | L postcentral gyrus BA 1/2 | −49, −12, 24 | 112 | .81 |
| R parahippocampus | 19, −45, −4 | 328 | .91 | |
| L cerebellar Lobes 3/4 | −10, −44, −26 | 104 | −.81 | |
| Midline posterior cingulate BA 29/30 | 0, −45, 12 | 608 | .83 | |
| L fusiform gyrus BA 19 | −35, −70, −16 | 96 | .80 | |
| MIDDLE: Block 5 | R inferior frontal gyrus BA 47 | 33, 19, −4 | 72 | .84 |
| L precentral gyrus BA 4/6 | −52, 2, 8 | 144 | .82 | |
| L hippocampus/parahippocampus | −32, −27, −8 | 704 | .90 | |
| R parahippocampus | 19, −40, −1 | 1,136 | .91 | |
| LATE: Block 8 | L precentral gyrus BA 4/6 | −50, 8, 8 | 72 | .77 |
| R superior temporal gyrus BA 22 | 47, −8, 1 | 208 | .85 | |
| L middle temporal gyrus BA 21 | −53, −26, −4 | 96 | −.83 | |
| L parahippocampus | −25, −38, −4 | 120 | .81 | |
| L posterior cingulate BA 29 | −4, −44, 10 | 112 | .78 | |
| R parahippocampus | 13, −55, −4 | 1,232 | .95 | |
| R middle occipital gyrus BA 19 | 41, −75, 18 | 96 | −.91 | |
| SWITCH: Block 11 | R middle frontal gyrus BA 9/46 | 28, 38, 28 | 80 | −.81 |
| L precentral gyrus BA 4/6 | −48, 2, 8 | 136 | .81 | |
| R superior temporal gyrus BA 22 | 50, −16, 0 | 272 | .85 | |
| R parahippocampus | 30, −17, −20 | 80 | .81 | |
| L postcentral gyrus BA 1/2 | −51, −20, 24 | 288 | .87 | |
| R parahippocampus | 13, −46, −4 | 2,592 | .94 | |
| L fusiform gyrus BA 19 | −35, −60, −10 | 368 | .88 |
Note. Scores on the Generation test were correlated to normalized regional cerebral blood flow (rCBF) throughout the whole brain for each of the implicit sequence learning conditions. Talaraich coordinates represent the point of highest correlation. R = right; L = left.