Table 5.
Multivariable Analysis of Time to Local Relapse for All Patients
| Parameter | P | Hazard for Local Failure |
|
|---|---|---|---|
| Estimate | 95% CI | ||
| Randomized treatment 50 Gy WBI, 0 Gy v 16 Gy | .0006 | 0.47 | 0.31 to 0.73 |
| Age, > 50 v ≤ 50 years | < .0001 | 0.42 | 0.28 to 0.65 |
| Systemic treatment, yes v no | .088 | 0.66 | 0.41 to 1.06 |
| Differentiation grade of the invasive tumor, high v low/intermediate | .026 | 1.67 | 1.06 to 2.62 |
| Differentiation grade of DCIS | |||
| High v low/intermediate | .96 | 1.02 | 0.54 to 1.93 |
| No DCIS v high | .39 | 0.80 | 0.48 to 1.33 |
| Margin of invasive tumor, not involved v involved | .33 | 0.78 | 0.49 to 1.27 |
Abbreviations: WBI, whole breast irradiation; DCIS, ductal carcinoma in situ.