Figure 1.

Differences of nephrogenesis between newborn WT and Trps1 KO mice. (A) Morphologic differences of the kidneys between newborn WT and KO mice. Paraffin sections of kidneys from newborn WT mice (a, c, and e) and KO mice (b, d, and f) were stained with hematoxylin and eosin (H&E; a through d) and then immunostained with an antibody for vimentin (e and f). c and d are higher magnification images of the boxed areas in a and b, respectively. Bars = 100 μm. (B) Comparison of the number of glomeruli and interstitial area in the kidneys of newborn WT and KO mice. Data are means ± SD for five samples. *P < 0.01.