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Branching of ureteric buds is affected by loss of Trps1. (A) Whole-mount in situ hybridization of Wnt9b and Wnt4 was performed using kidneys from E14.5 WT mice (a and c) and Trps1 KO mice (b and d). Bar = 200 μm. (B) Comparison of the length of ureteric bud and the number of cap mesenchyme in the kidneys of E14.5 WT and KO embryos. Data are means ± SD for four samples. *P < 0.01.
