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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Pediatrics. 2009 Jul 20;124(2):637–648. doi: 10.1542/peds.2008-2874

TABLE 4.

Medication and Treatment Associated With CLD and MDIs and PDIs at 24 Months' Postterm Equivalent

Medications and Therapies CLD, % MDI, % PDI, % N


<55 55–69 <55 55–69
Surfactant, first week
 Yes 53 11 11 10 16 809
 No 24 11 11 7 12 106
Methylxanthine
 Yes 43 11 11 9 15 787
 No 85 15 12 11 22 128
Hydrocortisone
 Yes 67 15 8 18 16 85
 No 47 11 11 9 16 830
Dexamethasone
 Yes 71 4 21 8 25 24
 No 49 11 11 9 15 821
Analgesics
 Yes 56 12 10 11 15 579
 No 37 10 12 7 17 336
Sedative
 Yes 57 18 15 8 20 200
 No 47 10 10 10 14 716
PDA treatmenta
 Ligation 69 16 10 11 21 127
 Indomethacin 53 10 12 11 15 349
 Neither 46 11 13 8 10 130
PDA treatmentb
 Yes 58 12 12 10 17 544
 No 37 10 10 8 14 371
Transfusionc
 Yes 52 12 11 8 16 842
 No 14 8 11 10 11 72

CLD included infants with and without MV (CMV or high-frequency ventilation).

a

Among those with a clinical or echocardiographic PDA diagnosis.

b

Among all infants.

c

Packed red blood cells during 3 or 4 separate weeks in the first postnatal month.