TABLE 6.
Epoch | Epoch, OR (95% CI) | ||
---|---|---|---|
Antenatal | Neonatal (First 28 d) | 36 wk PMA | |
Antenatal | |||
Gestational age 23–24 wk | 1.7 (1.00–3.1) | 1.4 (0.6–3.0) | 1.3 (0.7–2.8) |
Single mother | 2.3 (1.5–3.5) | 2.3 (1.5–3.5) | 2.3 (1.5–3.6) |
Preeclampsia or fetal indication | 2.0 (1.01–3.8) | 1.9 (0.96–3.8) | 1.9 (0.9–3.8) |
Neonatal (first 28 d) | |||
Late bacteremia | — | 1.8 (1.3–2.5) | 1.8 (1.3–2.5) |
Pneumothorax | — | 3.7 (2.6–5.4) | 3.6 (2.5–5.4) |
NEC ≥ stage II | — | 2.2 (1.3–3.7) | 2.1 (1.2–3.7) |
36 wk PMA | |||
CLD without MV | — | — | 1.1 (0.8–1.4) |
CLD with MV | — | — | 1.2 (0.7–2.3) |
These analyses include only those children without a severe gross motor impairment (GMFCS score < 1). Antenatal epoch includes the following variables: gestational age of 23–24 weeks; gestational age of 25–26 weeks; single mother; complete course of antenatal steroids; cesarean delivery; and delivery for preeclampsia or fetal indications. Neonatal epoch includes the following variables: SNAP-II in the top quartile; MV or high-frequency ventilation at 7 days; late bacteremia; pneumothorax; PIE; Pao2 in the lowest quartile (week 1); Pao2 missing (week 1); transfusions (packed red blood cells); PD; EPPD; ventriculomegaly; echolucent lesion; echodense lesion; NEC stage II or worse; methylxanthine; PDA; and PDA ligation. Thirty-six weeks' PMA epoch includes the following variables: CLD without MV (CMV or high-frequency ventilation) at 36 weeks and CLD with MV.