TABLE 7.
Epoch | Epoch, OR (95% CI) | ||
---|---|---|---|
Antenatal | Neonatal (First 28 d) | 36 wk PMA | |
Antenatal | |||
Single mother | 1.8 (1.02–3.0) | 1.8 (0.95–3.5) | 1.8 (0.9–3.5) |
Complete antenatal corticosteroids | 2.3 (1.5–3.5) | 2.4 (1.5–3.9) | 2.4 (1.5–3.8) |
Preeclampsia or fetal indication | 2.2 (1.5–3.1) | 2.3 (1.7–3.3) | 2.2 (1.5–3.2) |
Neonatal (first 28 d) | |||
Pneumothorax | — | 1.9 (1.1–3.5) | 1.9 (1.1–3.3) |
PIE | — | 2.2 (1.04–4.7) | 2.0 (0.99–4.2) |
PD | — | 3.6 (1.2–7.6) | 2.7 (1.1–6.5) |
EPPD | — | 3.0 (1.2–7.6) | 2.7 (1.1–6.5) |
36 wk PMA | |||
CLD without MV | — | — | 1.1 (0.6–2.0) |
CLD with MV | — | — | 1.9 (0.97–3.9) |
These analyses include only those children without a severe gross motor impairment (GMFCS score < 1). Antenatal epoch includes the following variables: gestational age of 23–24 weeks; gestational age of 25–26 weeks; single mother; complete course of antenatal corticosteroids; cesarean delivery; and delivery for preeclampsia or fetal indications. Neonatal epoch includes the following variables: SNAP-II in the top quartile; MV or high-frequency ventilation at 7 days; late bacteremia; pneumothorax; PIE; Pao2 in the lowest quartile (week 1); Pao2 missing (week 1); transfusions (packed red blood cells); PD; EPPD; ventriculomegaly; echolucent lesion; echodense lesion; NEC stage II or worse; methylxanthine; PDA; and PDA ligation. Thirty-six weeks' PMA epoch includes the following variables: CLD without MV (CMV or high-frequency ventilation) at 36 weeks and CLD with MV.