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(A and B) Representative resurgent currents recorded from a neuron expressing Nav1.6r (A) and Nav1.6r-I1477T (B) channels. Current traces are magnified ×20 and ×5, respectively, relative to the peak current. (C) Comparison of the relative resurgent current amplitude, expressed as a percentage of peak transient current, for wild-type and mutant VGSCs. *P < 0.05 versus the wild-type channel for the given isoform.
