Table 3.

Intrarenal gene expression during the early acute rejection and the risk of graft failure

	Variable	Hazard ratio	95% Confidence interval	P
AMR	TGF-β1 ≤ 2 (n = 11)	11.96	1.41 to 101.29	0.023
	RANTES ≤ 16.71 (n = 7)	5.61	1.38 to 22.73	0.016
	CD20 ≤ 5.7 (n = 5)	11.46	2.17 to 60.49	0.004
	FoxP3 ≤ 1.3 (n = 4)	6.38	1.41 to 28.89	0.016
TCMR	CD20 ≤ 31 (n = 8)	10.47	1.09 to 101.01	0.042

Low intragraft TGF-β1 (RQ ≤ 2), RANTES (RQ ≤ 16.71), CD20 (RQ ≤ 5.7), and FoxP3 (RQ ≤ 1.3) gene expressions in the biopsy with proved early AMR prior to the therapy and low intragraft CD20 (RQ ≤ 31) gene expression in the biopsy with proved early TCMR prior to the therapy were related with an increased risk of renal graft failure within the first 12 mo after kidney transplantation (univariate Cox regression model).