Table 4.
Basic patient characteristics
| AMR | TCMR | |
|---|---|---|
| N | 21 | 43 |
| Age (yr) | 47.0 ± 12.4 | 47 ± 10.7 |
| First/second/third transplants | 13/8/1 | 40/3/0 |
| Donor gender (male %) | 16/(76.2%) | 22/(51.2%) |
| Number of A mismatches | 1.1 ± 0.6 | 1.3 ± 0.6 |
| Number of B mismatches | 1.4 ± 0.6 | 1.3 ± 0.7 |
| Number of DR mismatches | 0.9 ± 0.7 | 1.0 ± 0.7 |
| PRA (%) | 44 ± 36 | 9 ± 16a |
| Hemodialysis duration (mo) | 35.1 ± 26.5 | 27.2 ± 26.5 |
| Immunosuppression: ATG or OKT3-Muromonab induction | 10 (47.6%) | 11 (25.6%) |
| Tacrolimus | 19 (90.5%) | 36 (83.7%) |
| CsA | 2 (9.5%) | 7 (16.3%) |
| MMF | 20 (95.2%) | 39 (90.7%) |
| SIR | 1 (4.8%) | 4 (9.3%) |
| Early AMR/TCMR: | ||
| Diagnosis (day) | 9.0 ± 2.8 | 8.6 ± 4.0 |
| Biopsy Cr (mg/dl) | 5.1 ± 2.8 | 4.4 ± 3.0 |
| Biopsy CCr (ml/min) | 27.7 ± 16.4 | 33.5 ± 19.0 |
| C4d+ (%) | 100 | 0 |
| CDCXM+ (%) | 90.5 | Not done |
| FXCM+ (%) | 90.5 | Not done |
| 12 months Cr (mg/dl) | 2.0 ± 0.8 | 1.7 ± 0.7 |
| 12 months CCr (ml/min) | 43.5 ± 17.8 | 61.9 ± 20.1b |
CCr, creatinine clearance; Cr, creatinine; SIR, sirolimus.
aP < 0.001.
bP < 0.05.