Table 1.
Characteristics of complicated and uncomplicated malaria patients
| Characteristics | Complicated malaria (110)a |
Uncomplicated malaria (169)a |
P-valueb |
|---|---|---|---|
| Agec(range) | 25.0 (14-67) | 24.0 (13-65) | 0.849 |
| Sex (male/female) | 75/35 | 133/36 | 0.137 |
| Nationalityd | |||
| Burmese | 17 (15.5) | 24 (14.2) | 0.614 |
| Karen | 18 (16.4) | 27 (16.0) | |
| Mon | 37 (33.6) | 72 (42.6) | |
| Thai | 38 (34.5) | 45 (26.6) | |
| Laos | 0 | 1 (0.6) | |
| Blood groupsd | |||
| A | 21 (19.1) | 27 (16.0) | 0.556 |
| AB | 6 (5.5) | 7 (4.1) | |
| B | 34 (30.9) | 58 (34.3) | |
| O | 47 (42.7) | 66 (39.1) | |
| NR | 2 (1.8) | 11 (6.5) | |
| Haemoglobin variants*d | |||
| Hb variants | 14 (12.7) | 29 (17.2) | 0.825 |
| Normal | 95 (86.4) | 133 (78.7) | |
| NR | 1 (0.9) | 7 (4.1) | |
| G6PD deficiencyd | |||
| Deficiency | 13 (11.8) | 14 (8.3) | 0.597 |
| Normal | 96 (87.3) | 153 (90.5) | |
| NR | 1 (0.9) | 2 (1.2) | |
| Parasitaemiae (range) | 117 322 (33-1 336 900) | 5641 (17-238 800) | <0.0001 |
| Highest fever°Cf | 38.1 ± 1.005 | 38.4 ± 0.981 | 0.011 |
| Haemoglobin g/df | 11.4 ± 0.24 | 12.1 ± 0.17 | 0.021 |
| Creatinine mg/dlf | 1.36 ± 1.21 | 0.88 ± 0.37 | <0.0001 |
| Glucose nmol/lf | 131.47 ± 62.06 | 118.17 ± 28.78 | 0.016 |
| Splenomegalyg | |||
| Positive | 18 (16.4) | 3 (1.8) | 0.039 |
| Negative | 92 (83.4) | 166 (98.2) | |
| Hepatomegalyg | |||
| Positive | 66 (60) | 32 (18.9) | < 0.0001 |
| Negative | 44 (40) | 137 (81.1) | |
| Previous malaria episodesd | |||
| Yes | 30 (27.3) | 93 (55.0) | < 0.0004 |
| No | 78 (70.9) | 76 (45) | |
| NR | 2 (1.8) | 0 |
a = Number of patients, b = Mann Whitney U or unpaired t test used for the analysis, c = Median, d = Percentages (in the parenthesis), e = Geometric mean/ml of blood, f = Mean ± SD, g = Percentages of individual with enlarged spleens and/or liver are in the parenthesis. *The Hemoglobin (Hb) variants includes HbE, HbF. NR = No report.