Table 5.
Complicated | Uncomplicated | ||||||||||
3-tiles of Ig levels | N | CC | CT | TT | P-value# | CC | CT | TT | P-value# | ||
Anti-Pf IgG1 | 274 | 5A | 46B | 53C | 11A | 67B | 84C | ||||
Anti-Pf IgG2 | 274 | 5 | 46 | 53 | 11 | 68 | 83 | ||||
Anti-Pf IgG3 | 276 | 5 | 46 | 53 | 11 | 68 | 85 | ||||
Anti-Pf IgE | 277 | 5 | 47 | 53 | 11 | 68 | 85 | ||||
Anti-PfIgG1* | Low | 0-14.47 | 91D | 0 | 20 | 26 | 0.395 | 2 | 23 | 16 | 0.118 |
Medium | 14.76-106.1 | 92 | 2 | 16 | 16 | 3 | 20 | 32 | |||
High | 107.2-1874 | 91 | 3 | 10 | 11 | 6 | 24 | 36 | |||
Anti-PfIgG2* | Low | 0.414-2.384 | 91 | 0 | 26 | 23 | 0.856 | 2 | 23 | 17 | 0.179 |
Medium | 2.386-6.617 | 92 | 3 | 12 | 22 | 3 | 19 | 29 | |||
High | 6.629-177 | 91 | 2 | 8 | 8 | 6 | 26 | 37 | |||
Anti-PfIgG3* | Low | 0.053-0.798 | 92 | 1 | 19 | 30 | 0.0054 | 3 | 20 | 16 | 0.079 |
Medium | 0.854-3.55 | 92 | 2 | 13 | 18 | 5 | 22 | 28 | |||
High | 3.629-119 | 92 | 2 | 14 | 5 | 3 | 26 | 41 | |||
Anti-Pf IgE** | Low | 0.015-0.3851 | 92 | 2 | 15 | 17 | 0.896 | 3 | 28 | 25 | 0.564 |
Medium | 0.3854-1.332 | 93 | 2 | 17 | 21 | 4 | 14 | 30 | |||
High | 1.346-29.05 | 92 | 1 | 15 | 15 | 4 | 26 | 30 |
N = Number of plasma for determining IgG1, IgG2, IgG3, IgE and genotyping IL4-590, # = Chi-squared test was used to test the difference of IL4-590 CC+CT and TT distribution between the low and high 3 tiles. * = μg/ml, ** = ng/ml, A = number of patients who carry IL4-590 CC genotype, B = number of patients who carry IL4-590 CT genotype, C = number of patients who carry IL4-590 TT genotype, D = Number of patients who had low, middle and high anti-P. falciparum -IgG1, -IgG2, -IgG3 and IgE levels.