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. 2009 Dec 10;8:286. doi: 10.1186/1475-2875-8-286

Table 5.

Association between IL4-590 genotype and anti-P. falciparum -IgG1, -IgG2, -IgG3 and IgE low or high tiled levels in patients with complicated and uncomplicated malaria.

Complicated Uncomplicated


3-tiles of Ig levels N CC CT TT P-value# CC CT TT P-value#


Anti-Pf IgG1 274 5A 46B 53C 11A 67B 84C
Anti-Pf IgG2 274 5 46 53 11 68 83
Anti-Pf IgG3 276 5 46 53 11 68 85
Anti-Pf IgE 277 5 47 53 11 68 85


Anti-PfIgG1* Low 0-14.47 91D 0 20 26 0.395 2 23 16 0.118
Medium 14.76-106.1 92 2 16 16 3 20 32
High 107.2-1874 91 3 10 11 6 24 36


Anti-PfIgG2* Low 0.414-2.384 91 0 26 23 0.856 2 23 17 0.179
Medium 2.386-6.617 92 3 12 22 3 19 29
High 6.629-177 91 2 8 8 6 26 37


Anti-PfIgG3* Low 0.053-0.798 92 1 19 30 0.0054 3 20 16 0.079
Medium 0.854-3.55 92 2 13 18 5 22 28
High 3.629-119 92 2 14 5 3 26 41


Anti-Pf IgE** Low 0.015-0.3851 92 2 15 17 0.896 3 28 25 0.564
Medium 0.3854-1.332 93 2 17 21 4 14 30
High 1.346-29.05 92 1 15 15 4 26 30

N = Number of plasma for determining IgG1, IgG2, IgG3, IgE and genotyping IL4-590, # = Chi-squared test was used to test the difference of IL4-590 CC+CT and TT distribution between the low and high 3 tiles. * = μg/ml, ** = ng/ml, A = number of patients who carry IL4-590 CC genotype, B = number of patients who carry IL4-590 CT genotype, C = number of patients who carry IL4-590 TT genotype, D = Number of patients who had low, middle and high anti-P. falciparum -IgG1, -IgG2, -IgG3 and IgE levels.