Table 1.
miRNA target genes are less compact
| miRNA target genes | Non-miRNA target genes | Fold difference | Rank order | |
|---|---|---|---|---|
| TargetScanS | n = 6444 | n = 12428 | ||
| Coding sequences length | 2009 ± 26 (1512) |
1575 ± 14 (1182) |
1.28 1.28 |
6 |
| 3'UTR length | 1730 ± 19 (1303) |
1251 ± 11 (498) |
1.38 2.62 |
1 |
| 5'UTR length | 274 ± 3 (214) |
197 ± 2 (131) |
1.39 1.63 |
3 |
| mRNA length | 3989 ± 33 (3460) |
2705 ± 19 (2161) |
1.48 1.60 |
4 |
| Total intron length | 83699 ± 1890 (35802) |
42275 ± 859 (14315) |
1.98 2.50 |
2 |
| Number of introns | 11.6 ± 0.14 (9) |
8.5 ± 0.01 (6) |
1.37 1.50 |
5 |
| PicTar | n = 6545 | n = 12327 | ||
| Coding sequences length | 1771 ± 22 (1346) |
1264 ± 13 (873) |
1.40 1.54 |
4 |
| 3'UTR length | 1688 ± 18 (1286) |
965 ± 12 (497) |
1.75 2.59 |
1 |
| 5'UTR length | 271 ± 3 (214) |
198 ± 2 (131) |
1.37 1.63 |
3 |
| mRNA length | 3871 ± 32 (3363) |
2757 ± 20 (2180) |
1.40 1.54 |
4 |
| Total intron length | 80741 ± 1792 (33818) |
43507 ± 910 (14564) |
1.86 2.32 |
2 |
| Number of introns | 11.1 ± 0.14 (9) |
8.5 ± 0.09 (6) |
1.28 1.50 |
5 |
| RNA22 | n = 9055 | n = 9817 | ||
| Coding sequences length | 1833 ± 20 (1398) |
1622 ± 16 (1191) |
1.13 1.17 |
5 |
| 3'UTR length | 1415 ± 14 (976) |
1032 ± 14 (499) |
1.41 1.96 |
1 |
| 5'UTR length | 231 ± 2 (171) |
216 ± 3 (149) |
1.07 1.15 |
6 |
| mRNA length | 3455 ± 26 (2898) |
2856 ± 23 (2240) |
1.21 1.29 |
4 |
| Total intron length | 61231 ± 1201 (25368) |
51983 ± 1250 (14451) |
1.18 1.76 |
2 |
| Number of introns | 11.6 ± 0.1 (8) |
8.8 ± 0.1 (6) |
1.32 1.33 |
3 |
Comparison of the structure parameters of non-miRNA target genes with those of miRNA target genes predicted from TargetScans, PicTar, and RNA22. For each gene structure parameter the first line gives the average value ± s.e.m, and the 2nd line the median values in brackets. n: the number of genes in each category. The median lengths of miRNA target genes were significantly longer (one-side Wilcoxon rank sum test p < 10-250) than those of non-miRNA target genes in all parts of gene structures.