Table 1.

Differentially coexpressed modules

module	size	cor_WT	p_WT	cor_h	p_h	cor_t	p_t	function
		coexpressed		coexpressed		not coexpressed
35	27	0.33	0.02	0.13	0.02	0.02	0.33	cell adhesion
93	13	0.26	0.13	0.20	0.01	0.01	0.49	growth factor binding
		coexpressed		not coexpressed		not coexpressed
51	19	0.35	0.01	0.01	0.47	0.02	0.44	metabolic processes
		not coexpressed		coexpressed		coexpressed
5	92	0.05	0.37	0.04	0.05	0.01	0.09	acute immune response
40	25	0.00	0.8	0.07	0.05	0.10	0	integrin complex
54	18	0.06	0.68	0.08	0.11	0.05	0.14	immune response
131	11	0.18	0.32	0.09	0.14	0.10	0.08	ephrin receptor
		not coexpressed		not coexpressed		coexpressed
14	40	0.07	0.51	0.01	0.36	0.05	0.03	respiratory chain
30	29	0.11	0.49	-0.03	0.98	0.05	0.06	signaling
65	16	0.16	0.9	0.05	0.42	0.11	0.11	nucleotide biosynthesis
69	15	0.02	0.76	-0.02	0.64	0.06	0.13	DNA repair
80	14	0.18	0.66	0.00	0.55	0.20	0.01	ER-Golgi transport
129	11	0.02	0.75	-0.06	0.72	0.09	0.13	hormone activity
		coexpressed		not coexpressed		coexpressed
13	40	0.20	0.02	0.01	0.38	0.05	0.02	aminoacid metabolism
18	38	0.23	0.01	-0.01	0.6	0.10	0	energy metabolism
22	36	0.32	0.02	-0.03	0.91	0.09	0	ATPase
24	34	0.38	0.03	0.00	0.63	0.12	0	lysosome
33	28	0.50	0	0.01	0.34	0.03	0.11	protein transport
37	27	0.22	0.04	0.02	0.31	0.10	0.02	ribosome, DNA methylation
38	26	0.19	0.06	-0.02	0.74	0.11	0	chromatin
42	24	0.32	0	-0.01	0.54	0.06	0.03	tRNA synthetase
70	15	0.38	0.05	-0.06	0.95	0.07	0.1	protein degradation
83	14	0.42	0.04	-0.07	0.82	0.06	0.14	translation termination
		not coexpressed		coexpressed		not coexpressed
74	15	0.11	0.72	0.18	0.07	0.02	0.59	Cu transporter
90	13	-0.06	0.96	0.15	0.08	-0.01	0.73	GABA receptor
102	12	-0.08	0.98	0.16	0.11	0.02	0.46	immune response
110	11	0.08	0.96	0.20	0.03	-0.06	1	coagulation

Network modules whose coexpression differs between disease stages. Average value for Pearson's Correlation Coefficient in the module, and corresponding p-value in healthy (5 samples), hyperplastic (4 samples) and cancer samples (15) are shown (cor_WT, p_WT, cor_h, p_h, cor_t, and p_t, respectively). Significant coexpression was declared based on the p-value (threshold of p-value < 0.15: coexpressed; p-value > 0.3: not coexpressed).