Table 7.
Dose range | Site | Φm |
LRT2p-con at Φm |
LRT2p-lin at Φm |
ERR1 at Φm |
Latency Range |
ERR0.025 at Φm |
Latency Range |
---|---|---|---|---|---|---|---|---|
0-20 | Stom | 11 | 13.02 p = 0.007 |
12.27 p = 0.003 |
0.38 (0.11, 0.70) (0.16, 0.65)* |
5-18 5-21* 9-21nl |
0.34 (0.11, 0.63) (0.14, 0.59)* |
5-21 5-21* |
5-500 | Stom | 8 | 9.03 p = 0.025 |
5.74 p = 0.07 |
0.29 (0.06, 0.60) (0.09, 0.55)* |
7-9 5-11* |
||
0-20 | Liver | 37 | 28.41 p < 10-7 |
18.96 p < 10-4 |
1.26 (0.61, 2.14) (0.69, 1.97)* |
29-43 29-43* 29-41nl |
0.68 (0.18, 1.25) (0.24, 1.20)* |
29-44 29-44* |
5-500 | Liver | 37 | 14.47 p = 0.003 |
10.55 p = 0.005 |
0.74 (0.25, 1.43) (0.32, 1.30)* |
34-41 34-42* 34-41nl |
||
0-20 | Lung | 16 | 10.43 p = 0.03 |
7.13 p = 0.05 |
1.00 (0.36, 1.84) (0.42, 1.72)* |
10-21 10-21* 12-16nl |
0.80 (0.21, 1.66) (0.28, 1.53)* |
10-16 10-21* |
5-500 | Lung | 16 | 21.69 p < 10-4 |
19.63 p < 10-5 |
1.33 (0.67, 2.22) (0.73, 2.10)* |
7-21 7-21* 12-21nl |
||
0-20 | Panc | 10 | 14.89 p = 0.002 |
13.7 p < 0.001 |
11.32 (5.35, 16.46) (5.44, 15.60)* |
5-11 5-11* 7-11nl |
10.77 (4.21, 16.05) (4.70, 15.31)* |
5-11 5-11* |
5-500 | Panc | 42 | 1.97 p = 0.64 |
1.96 p = 0.38 |
0.44 (-, -) | - | ||
0-20 | Leuk | 25 | 21.66 p < 10-4 |
21.66 p < 10-5 |
1.39 (0.09, 4.31) (0.26, 3.79)* |
24-25 24-26* 17-36nl |
0.89 (0.11, 2.22) (0.16, 2.16)* |
19-33 17-33* |
5-500 | Leuk | 28 | 14.76 p < 0.001 |
8.60 p = 0.013 |
1.83 (0.45, 3.92) (0.59, 3.66)* |
24-31 24-32* 24-28nl |
Dose range: data on which the two-phase model is fitted, including "city" as a control covariate
Φm: latency, restricted to integers 5, 6,... 44, which maximises LRT2p-con subject to ERR1 ≥ 0
LRT2p-con: Likelihood Ratio Test comparison of two-phase and control models at Φm. p values derived from Table 8
LRT2p-lin: Likelihood Ratio Test comparison of two-phase and linear models at Φm. p values derived from Table 8
ERR1: Excess Relative Risk at 10 mSv, from the two-phase model fitted across the dose range with latency Φm, and its BCa 95%CI (5000 replications)
Latency range: integral latency range around Φm for which BCa 95%CI is strictly positive
*: BCa 90%CIs (5000 replications)
nl: integral latency range around Φm for which LRT2p-lin > 6
ERR0.025: as above, for 0.25 mSv (computed only when Dose range = 0-20 mSv)