Table 8.

simulated null distribution of LRT_2p-con and LRT_2p-lin including "city", by dose range

Dose range	Site	Φm	LRT2p-con Shape	LRT2p-con Rate	t0.95	LRT2p-lin shape	LRT2p-lin rate	T0.95
0-20	Stom	11	2.38	0.59	9.06	1.98	0.65	7.25
5-500	Stom	8	2.03	0.62	7.72	1.30	0.55	6.42
0-20	Liver	37	2.50	0.73	7.63	1.69	0.64	6.58
5-500	Liver	37	1.62	0.49	8.39	1.14	0.53	6.16
0-20	Lung	16	2.47	0.58	9.43	2.09	0.68	7.20
5-500	Lung	16	1.81	0.61	7.26	1.38	0.66	5.58
0-20	Panc	10	2.35	0.61	8.65	2.13	0.71	6.93
5-500	Panc	42	1.72	0.52	8.18	1.18	0.60	5.61
0-20	Leuk	25	2.11	0.62	7.94	1.59	0.67	6.01
5-500	Leuk	28	1.87	0.62	7.34	1.25	0.56	6.14

gamma distributions are fitted to 500 simulations of LRT_2p-con for the null hypothesis (β₀,σ₀,τ₀) = (0,0, arbitrary) and of LRT_2p-lin for the null hypothesis (β₀,σ₀,τ₀) = (,0, arbitrary) where is the fitted parameter for the linear model. Models include "city" as a control covariate and are fitted at the optimal (integral) latency Φ_m for the site and dose range.

shape: shape parameter of the fitted gamma distribution

rate: rate parameter of the fitted gamma distribution

t_0.95: critical value of the fitted gamma distribution for

T_0.95: critical value of the fitted gamma distribution for