Table 3.

IC₅₀ and EC₅₀ values reported for binding/activation of steroid receptors by their natural ligands.

Receptor	IC50 (M)	EC50 (M)
ER	8.99 × 10−10a	1.76 × 10−11b
AR	7.7 × 10−10c	3.90 × 10−10d
PR	4.00 × 10−9e	2.30 × 10−7f
AhR	6.4 × 10−11g	4.88 × 10−11h

ER binds 17β-estradiol, AR binds DHT, progesterone receptor (PR) binds progesterone, and AhR binds TCDD.

^aData from Blair et al. (2000).

^bData from Pillon et al. (2005).

^cData from Cabeza et al. (2004).

^dData from Xu et al. (2005).

^eData from Viswanath et al. (2008).

^fData from Lenasi and Breskvar (2004).

^gData from Bonefeld-Jørgensen et al. (2007),

^hData from Westerink et al. (2008).