Table 4.
Variable | Wt Loss < 7% (n=17) |
Wt Loss ≥ 7% (n=11) |
P-values |
---|---|---|---|
Baseline Characteristics | |||
BMI Category, N (%) -overweight (25- 29.9 kg/m2) -obesity class I (30- 34.9 kg/m2) -obesity class II (35- 40 kg/m2) |
5 (26.3) 5 (26.3) 9 (47.4) |
3 (27.3) 6 (54.5) 2 (18.2) |
0.21 |
Diabetes, N (%) | 10 (52.6) | 4 (36.4) | 0.39 |
On metformin, N (%) |
7 (36.8) | 2 (18.2) | 0.28 |
Histologic Parameters | |||
Fat (0-3) |
−0.41 (0.80) | −1.36 (0.67) | <0.001 |
Lobular inflammation (0-3) |
−0.24 (0.75) | −0.82 (0.75) | 0.03 |
Ballooning Injury (0-2) |
−0.53 (0.80) | −1.27 (0.47) | 0.03 |
Fibrosis (0-4) |
+ 0.06 (0.83) | −0.45 (0.93) | 0.10 |
NAS (0-8) |
−1.18 (1.59) | −3.45 (1.21) | <0.001 |
Participants with ≥3 points improvement in NAS from baseline, N (%) |
4 (23.5) | 9 (81.8) | 0.003 |
Participants with NAS ≤2 at follow up, N (%) |
4 (23.5) | 10 (90.9) | <0.001 |