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. 2010 Jan 11;5(1):e8658. doi: 10.1371/journal.pone.0008658

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Spigoni et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A–D) Within the E12.5 developing CNS, Emx2OS-ncRNA is detectable in telencephalon (A,B), mesencephalon (me), including both tectum (te) and tegmentum (tg), (panels A,C) and diencephalon, including the mammillary recess (arrowhead in panel A). It is not present in rhombencephalon (rh, panel G), except the choroid plexus of the IV ventricle (chp, panels A,D). Outside the CNS, Emx2OS is expressed in primordia of sense organs, nasal pits (np, panel E) and otic vesicle (ov, panel G), as well as in mesenchyme underlying snout epidermis (A, asterisk) and surrounding the hypothalamic (hy) optic recess (F, arrowheads). Scalebars, 200 µm in A–C, 50 µm in D–G.