Fig. 4.

Differences between the working group (WG) assessment and statistical analyses based on different methods and data pretreatment. a Differences between the WG assessment and the combination test (chi-square plus ISM-PBE). b Differences between the WG assessment and the OPLS analysis based on unit-variance scaling on absolute mass data. c Same as 4b except that Pareto scaling was used. d Same as 4b but absolute mass data was first normalized to percent mass data. e Same as 4d but Pareto scaling was used. The working group evaluation and possibility of equivalence from the combination test were retrieved from Ref. (14)