Table I.
Composition of Various Mucoadhesive Buccal Tablets of Ondansetron
| Batch code | 5% CP 934 (mg) | 10% CP 934 (mg) | 15% CP 934 (mg) | 20% CP 34 (mg) | HPMC 15 cps (mg) | SCMC LV (mg) | Sod. alg. (mg) | OH (mg) | Magnesium stearate (mg) | Aspartame (mg) |
|---|---|---|---|---|---|---|---|---|---|---|
| C1 | 10 | 185 | 5 | 1.5 | 2 | |||||
| C2 | 20 | 175 | 5 | 1.5 | 2 | |||||
| C3 | 30 | 165 | 5 | 1.5 | 2 | |||||
| C4 | 40 | 155 | 5 | 1.5 | 2 | |||||
| C5 | 10 | 185 | 5 | 1.5 | 2 | |||||
| C6 | 20 | 175 | 5 | 1.5 | 2 | |||||
| C7 | 30 | 165 | 5 | 1.5 | 2 | |||||
| C8 | 40 | 155 | 5 | 1.5 | 2 | |||||
| C9 | 10 | 185 | 5 | 1.5 | 2 | |||||
| C10 | 20 | 175 | 5 | 1.5 | 2 | |||||
| C11 | 30 | 165 | 5 | 1.5 | 2 | |||||
| C12 | 40 | 155 | 5 | 1.5 | 2 |
OH ondansetron hydrochloride, CP carbopol-934, SCMC LV sodium carboxymethyl cellulose low viscosity, HPMC 15cps hydroxypropylmethylcellulose 15cps, sod. alg. sodium alginate