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. 2009 Sep 9;10(4):1093–1103. doi: 10.1208/s12249-009-9306-2

Table II.

Variables and Their Corresponding Levels Implemented for the Construction of Box–Behnken Design

Code Independent variables (w/w) Levels
Low (−1) Medium (0) High (+1)
X 1 Carbopol content 0.75 1.0 1.25
X 2 Capryol 90 concentration 5.0 7.5 10
X 3 Drug concentration 0.5 0.6 0.7