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. 2009 Oct 24;10(4):1178. doi: 10.1208/s12249-009-9309-z

Table I.

Operative Conditions, Viscosity at Nozzle, and Mean Diameter of Beads Manufactured by Prilling

Sodium alginate solution (%, w/w) Flow rate (ml/min) Viscosity at nozzle (m Pas) Frequency of vibration (Hz) Mean diameter (µm)
Ketoprofen/Polymer
1:10 0.50 15 24 ± 0.9 250 745 ± 19
1:5 15 26 ± 1.2 250 748 ± 21
1:3 15 27 ± 1.1 250 753 ± 21
1:10 1.50 18 73 ± 2.6 250 742 ± 25
1:5 18 75 ± 2.4 250 749 ± 26
1:3 18 76 ± 2.4 250 751 ± 19
1:10 2.50 15 356 ± 9.5 280 748 ± 36
1:5 15 358 ± 9.9 280 754 ± 33
1:3 15 362 ± 9.8 280 751 ± 36
Ketoprofen lysinate/Polymer
1:10 0.5 15 29 ± 1.3 250 746 ± 29
1:5 20 36 ± 1.8 250 755 ± 32
1:3 20 49 ± 1.6 250 752 ± 31
1:2 20 85 ± 2.6 250 751 ± 28
1:1 20 118 ± 3.4 250 748 ± 32
1:10 1.50 20 74 ± 2.8 250 752 ± 23
1:5 20 126 ± 4.3 250 754 ± 28
1:3 18 180 ± 4.8 250 756 ± 25
1:2 15 250 ± 6.6 270 749 ± 42
1:1 15 395 ± 8.4 290 754 ± 43
1:10 2.50 15 370 ± 7.9 280 748 ± 41
1:5 15 446 ± 9.3 300 749 ± 46
1:3 15 575 ± 9.9 320 752 ± 43
1:2 18 768 ± 12.3 380 755 ± 50
1:1 15 986 ± 15.9 450 756 ± 52

Each point represents the mean ± SD (n = 3)