Table V.
Fitting of Drug Release from Optimized Solid Dispersion to Various Release Kinetic Models
Mechanism | Zero-order | First-order | Higuchi | Hixson–Crowel | Korsemeyer | |||||
---|---|---|---|---|---|---|---|---|---|---|
Slope | r 2 | Slope | r 2 | Slope | r 2 | Slope | r 2 | Slope | r 2 | |
Optimized formula | 0.3724 | 0.6559 | −0.003 | 0.8169 | 0.0878 | 0.9197 | 0.0064 | 0.8761 | 0.2091 | 0.9463 |