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. 2009 Oct 28;10(4):1206–1215. doi: 10.1208/s12249-009-9316-0

Table V.

Fitting of Drug Release from Optimized Solid Dispersion to Various Release Kinetic Models

Mechanism Zero-order First-order Higuchi Hixson–Crowel Korsemeyer
Slope r 2 Slope r 2 Slope r 2 Slope r 2 Slope r 2
Optimized formula 0.3724 0.6559 −0.003 0.8169 0.0878 0.9197 0.0064 0.8761 0.2091 0.9463