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Effect of compression force on diltiazem release from alginate matrix tablets prepared with different hardness. Open circles 3.5 kgf (F7), open triangles 4.5 kgf (F8), filled circles 5.5 kgf (F9), filled triangles 6.5 kgf (F10). Each data point is the mean of four determinations (maximum SEM ±6.87%)
